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Symptom
or Side Effect?
The
Side Effects of Psychiatric Drugs
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By
Karima Burns, MH, ND
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24/04/2002
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Children
with ADHD have been treated with Ritalin for decades. |
Andrea
Yates, famed for drowning her five small children last year, was taking five
different psychiatric drugs at various times. Eric Harris, the student
responsible for the Columbine school killings was on a Prozac-like drug, Luvox,
at the time of the killings. Fifteen-year-old Shawn Cooper was on Ritalin when
he fired a gun at his school (Breggin 2000).
Dr.
Park Dietz, a consultant for the Andrea Yates trial stated of her situation,
“Escape is something she couldn't admit she needed. She doesn't have the skill
to say, `I'm out of here. Get me a baby sitter and a new house,’”
(Christian). She took drugs instead. Andrea Yates, seemed even to use the drugs
to her advantage. When she did not get attention or help from her husband, being
on medication gained her sympathy. Taking an overdose got her a new home. Dietz,
like other people, laid blame on Andrea for either not asking for enough help or
not taking her medication. However, few have thought to consider that her
medication may have had a role in her horrible acts. And few people realize or
would readily admit that they abuse psychiatric drugs in the same way she did.
Peter
Breggin, in his book Reclaiming Our Children, has found that many of the
children who did school killings were on psychiatric drugs such as Prozac,
Ritalin or (as he states) “the most toxic agents of all, the adult
anti-psychotic drugs Haldol, Risperdal and Zyprexa.” Interestingly enough, the
articles about Andrea Yates state that the Haldol she had been taking “did not
produce any side effects of psychosis.” However, Peter Breggin and numerous
scientific studies refute that opinion. Andrea Yates had been taking Effexor,
Remeron, Wellbutrin and Haldol. Family members blamed her problems on not taking
enough medication. However, a little research shows that taking medication may
actually be more dangerous than not taking it.
The
main problems with physiciatric drugs are that they are often given too soon,
for the wrong reasons and while their few questionable benefits are touted
widely in ads, articles and press-releases, their side-effects are largely
hidden or ignored. Lisa Schizandra of Theotherside.com has compiled a list
of resources and articles on anti-depressants and other psychiatric drugs and
has found that in the clinical trials that the drug was barely distinguishable
from the placebo, that people often are cured for other reasons other than the
drug, that they do not work and have not been tested widely on children, they
can cause suicidal symptoms in some people and that they are relatively toxic to
many people.
Many
times, drugs are given too soon or for the wrong reason. Many drugs are given
according to a person’s answers to a list of questions that show they exhibit
the required symptoms. However, often these symptoms can be mimicked by other
health problems or temporary lifestyle challenges - such as a move or lack of
sleep. Peter Breggin has found that when there is conflict in the home, divorce,
inadequate parenting or discipline skills, a child will often develop all the
symptoms of attention Deficit/Hyperactivity Disorder (ADHD). Similarly, if one
combines post-partum hormonal problems with the difficulty of raising small
children and a baby, an unhelpful husband and perhaps even a history of marital
conflict, the symptoms often mimic those of post-partum depression.
In
fact, sleep-deprivation alone can mimic depression and a number of psychiatric
conditions. Oftentimes, simply getting more sleep can alleviate symptoms in
these cases. This is, ironically, most obvious in the clinical trials of the
major psychiatric drugs on the market today. Over six weeks of treatment, a
majority of patients do improve, according to the trials conducted for Food and
Drug Administration (FDA) approval. As measured by the Hamilton Depression
scale, the scores drop about 40 percent. While far from a cure, this is a marked
improvement. But as noted in studies, patients getting a placebo improved by a
similar amount (Moore).
Reviews
of medical journals have continuously and consistently found that modern
psychiatric problems are usually resolved within six weeks without the use of
any drugs. In fact, Schizandra found that, “In many clinical trials for
FDA approval the difference between drug and placebo was about two points on a
0-50 scale measuring depression. In a study of the five popular drugs, more than
80% of the benefit was duplicated in a similar group getting a placebo” (Schizandra).
Thomas Moore, a journalist at The Boston Globe dug into the FDA archives with a
respected scientist as his assistant and found that, “If one combines all the
Prozac studies in FDA files, it becomes clear that nearly 90% of the
improvements reported by patients taking Prozac were also reported by the
patients taking placebos.” And that, “Prozac is not the only antidepressant
to post marginal benefits in clinical trials” (Moore).
What
is startling is that sometimes anti-depressants or drugs are prescribed before
other methods are tried to help the person and some psychiatrists use the drugs
as a catalyst for change rather than as a last resort. But sometimes this
catalyst backfires. All of the modern Psychiatric drugs have side effects and
most people taking these suffer from at least some of the side effects.
Unfortunately, once a person starts taking the drugs it is sometimes hard to
tell the difference between side-effects and the original problem - so problems
can become worse on medication and are often combated by increasing dosage or
changing medication rather than considering the side-effects of the original
medication (Moore).
Prozac,
according to Eli Lilly, causes rashes or hives in 7% of the people who take it,
insomnia in 20%, sedation in 13%, tremors in 10%, nausea in 23%, diarrhea in
12%, and loss of appetite in 12%. Because it was not well studied during
testing, sexual dysfunction was understated in the official ranking. Depending
on definitions, from 10 to 70% find their sex lives diminished.
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Many
drugs are given to patients for the wrong reasons. |
To
make the situation worse, in many clinical trials the definition of success is
very opinionated. What some doctors define as success, others may define as a
failure. Peter Breggin, in his research on drug reactions has found that in
studies the following were shown to be positive effects of the drugs:
stereotypical activities, compulsive disorders, inflexibility of thinking,
over-focusing, social withdrawal and isolation, diminished play, increased
solitary play, depression, frequent crying, bland emotionless behavior, and
drowsiness (Breggin, 2002). Furthermore, studies are often slanted from the
beginning as many people drop out before they complete the study. Schizandra
found that, “ In testing, from 15% to 21% quit because of intolerable
side effects, and a majority are either over stimulated [insomnia, anxiety], or
get detached, listless, tired or feel sedated. Another 10% suffer signs of
neurological impairment, including tremors, twitches, and tics.” Final study
results are based only on those people that complete the study.
Moore
reports that, “A recent federal study of 315 published clinical trials of 29
antidepressant drugs noted that every one which identified a sponsor came from a
drug company. While the FDA requires companies to submit failed trials, reports
of drugs with no effect seldom make it to the medical journals.” For
example, one published trial of Serzone with a marginal result matches the FDA
records. But an identical trial with no measurable drug effect did not get
published, according to the federal study. How many drug companies are going to
publish a study that makes their drug look bad? (Moore).
Peter
Breggin, in his article, “Confirming the Hazards of Stimulant Drug
Treatment”, notes that one reason harmful side-effects of psychiatric drugs
have been ignored is that there is very little motivation to perform and then
publish studies on these side-effects. He states that, “Until recently, no
studies have systematically examined the rate of psychotic symptoms caused by
routine treatment with stimulant drugs such as methylphenidate [Ritalin] and
amphetamine [Dexedrine, Adderall]. Doctors who prescribe stimulant drugs
often seem oblivious to the fact that they can cause psychoses, including
manic-like and schizophrenic-like disorders. Without providing a
scientific basis, the literature often cites rates of 1% or less for
stimulant-induced psychoses” (Breggin, 1998).
Recent
studies have shown that in children with ADHD, up to 9% showed marked psychosis
at the beginning of treatment and that when treatment with drugs stopped, the
psychosis vanished. It also showed that in children not taking drugs there were
absolutely no cases of psychosis (Breggin 2002). Furthermore, the authors of the
study concluded that, due to poor reporting, the rate of stimulant-induced
psychosis and psychotic symptoms was probably much higher.
Breggin
reports on the dangers of these side-effects and says that “When these
children developed depression, delusions, hallucinations, paranoid fears and
other drug-induced reactions while taking stimulants, their physicians
mistakenly concluded that the children suffered from "clinical
depression," "schizophrenia" or "bipolar disorder" that
has been "unmasked" by the medications. Instead of removing the
child from the stimulants, these doctors mistakenly prescribed additional drugs,
such as antidepressants, mood stabilizers, and neuroleptics. Children who were
put on stimulants for "inattention" or "hyperactivity" ended
up taking multiple adult psychiatric drugs that caused severe adverse effects,
including psychoses and tardive dyskinesia.”
Peter
Breggin suggests that instead of asking “What can I do to fix this problem?”
that we start asking, “How can I change to adapt to and help this person who
has a problem?” As Muslims, we can also follow the example of the prophet
Muhammad and turn to herbs or natural remedies to assist us. Many herbs such as
skullcap, valerian, hops, catnip, and St. John’s Wort have proven effective in
many cases of ADHD and many types of depression. The side effects of these
natural remedies are mild and can be easily controlled by dosage.
Sources:
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Breggin,
Peter R., MD. "Confirming the Hazards of Stimulant Drug
Treatment." Center for Study of Psychiatry and Psychology. 2002.
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Breggin,
P. “Talking Back to Ritalin.” Monroe, Maine: Common Courage Press.
1998.
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Breggin,
P. “Psychostimulants in the treatment of children diagnosed with ADHD:
Risks and mechanism of action.” International Journal of Risk and
Safety in Medicine, 12, 3-35. 1999.
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Breggin,
P. “Reclaiming Our Children.” Cambridge, Massachusetts: Perseus
Books. 2000.
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Breggin,
P. Adverse Reactions to Stimulant Drugs Mistakenly Identified as
Beneficial.” Data from Twenty Controlled Trials.
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Breggin,
P. and Cohen, D. Your Drug May Be Your Problem: How and Why to Stop Taking
Psychiatric Medications. Cambridge, Massachusetts: Perseus Books.
1999.
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Cherland,
E. and Fitzpatrick, R. “Psychotic Side Effects of Psychostimulants: A
5-year Review.” Canadian Journal of Psychiatry, 44, 811-813. October
1999.
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Schizandra,
Lisa. “Prozac, Paxil and Zoloft – Oh My!” The Other Side Resource.
2001.
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Moore,
Thomas J. “No Prescription for Happiness.” The Boston Globe. 10/17/99.
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Christian,
Carol. “4 Yates Children Still Alive When Put to Bed.” Houston
Chronicle. 03/09/2002. 
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