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DNA
Data Bank... From Anthrax Letters to Bin Laden Genes
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By
Wagdy A. Sawahel, Ph.D., EurBiol.
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04/04/2002
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Detainee
held captive at U.S. military base on Cuba |
Although
Afghan captives being held at Camp X-Ray and in Afghanistan have had their
fingerprints, photographs and hair samples taken, American officials now want
samples of their DNA as well. American officials have proposed the development
of a DNA data bank of detainees by analyzing their blood samples for
identification purposes as well as tracking terrorism suspects in the future.
However,
although DNA is an excellent means of identification and is relatively simple to
isolate and compare, the results are never 100% certain and the possibilities
are almost endless. We leave skin cells containing DNA everywhere we go and on
every thing we touch, so, in theory, a forensic scientist could prove that we
had been there. In addition, some experts raise questions about the reliability
of DNA evidence and, therefore, fear that the innocent will be wrongly
convicted.
Gene
Bank Development & Uses
The
development of a gene bank involves isolating the DNA molecule from a cell,
which is then treated with enzymes to break it into pieces. These are separated
using an electric current, and the pattern of the separated fragments is used to
compare samples. In theory, all that is needed to extract DNA is one cell. This
cell can come from a speck of blood, a swab of saliva or even a miniscule
fragment of skin that clings to a strand of hair. But a more reliable match can
be made when a larger sample is available – at least one-thousandth the size
of a salt grain, invisible to the naked eye yet able to be separated and
matched.
The
proposed DNA profiles would most likely to be stored in a computer retrieving
system so they can be called up and compared with DNA samples taken from a
current criminal case.
DNA
Data Bank Of Terrorism Suspects… How Feasible Is It?
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USS
Cole after being bombed in Aden, Yemen |
Frustrated
by their inability to identify a vast majority of captured fighters of Al-Qaeda
and the Taliban, U.S. federal authorities are proposing to establish a DNA data
bank of terrorism suspects by analyzing blood samples from thousands of
detainees being held in Afghanistan and Cuba.
The
information could also play a role in some current investigations, including the
case of Richard Reid, who has been accused of trying to blow up a trans-Atlantic
flight in December 2001 with explosives hidden in his shoes. Investigators
discovered two human hairs embedded in a crude igniting device found in Mr.
Reid’s shoes. The authorities said that the strands did not match Mr. Reid’s
hair and that if a DNA database existed, analysts could search it for a match
and perhaps identify an accomplice.
However,
although it is increasingly accurate, DNA testing is not foolproof. DNA samples
can be stored at –80 oC in a test tube about the size of the top
joint of a thumb. As a result of long-term DNA storage, spontaneous changes can
occur. In addition, the tests may fail to make an accurate match if the DNA
sample was contaminated at the scene of the crime. Although the chances are
remote, the more DNA sample you get in the data bank, the greater the chance
that you find two samples that look the same but are not actually from the same
person. An investigation could be complicated if, for example, the prime suspect
has a twin. The pair will have either identical or very similar genetic
profiles.
If a suspect drank from a glass left at the crime scene, scientists can test for
skin cells from their lips. Even a fingerprint can be tested if skin cells from
the offender’s finger are left behind. But the collected sample could also
have been a cell left lounging around on the surface before the offender put
their finger on the same place. So there is always the question “did it really
come from that person”? Science can still not be 100% certain.
The
total DNA makeup is unique to an individual and can be matched up with the
person from whom it originated. However, in forensic investigation only
fragments of the DNA from a cell are compared and not the entire strand. Because
of this, there is the possibility that more than one person might have the same
pattern for such a fragment.
Current
Investigations Using DNA
Some
victims from the World Trade Center attacks were identified after DNA evidence
collected from toothbrushes, hairbrushes and other belongings of those lost in
the wreckage was compared with samples gathered from victim’s families.
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Identification
of the Source of Anthrax Strain
Although
anthrax was traced to the Ames American strain of bacteria, first isolated in
Iowa and maintained by U.S. Army and Central Intelligence Agency (CIA) since
1980, discovering the genetic sequencing could reveal the age of the deadly
strain sent in the letters and might lead investigators to the laboratory where
it was produced. However, even that genetic information might not be enough to
turn up a suspect because so many scientists have access to anthrax for research
purposes. In addition, the Federal Bureau of Investigation (FBI) confirmed that
they are investigating the loss or theft of more than two-dozen potentially
dangerous biological samples, including anthrax microbes in 1991 from the
military labs at Fort Detrick.
U.S.
officials do not believe that Osama bin Laden is dead but they want to rule out
definitively that the al-Qaeda leader was not killed in a recent missile strike
in Zawar Kili in Afghanistan on February 4, 2002. Although local Afghan
villagers said that the victims were innocent Afghans, the armed forces
pathology lab is examining human remains to determine the identities of the
people killed in the missile strike. One of the people killed in the strike has
been described as tall, dressed in Arab white robes, and treated with deference
by others, leading to speculation that it could have been bin Laden.
The
United States is trying, through intermediaries, to obtain DNA samples, from
members of Bin Laden’s family for comparison with forensic evidence, if
needed. There could be many possible DNA donors; bin Laden’s father, now dead,
had 54 children by several wives.
Investigation
of the USS Cole Bombing in Yemen
On
October 12, 2000, bombers in a small, explosives-laden boat approached American
battleship the USS Cole while it was refueling in Aden harbor in Yemen and
detonated the explosives, ripping a 60-by-40-foot hole in the steel hull. The
blast killed 17 American sailors and injured 39. U.S. officials are trying
to get a DNA sample from the colleted human remains - such as teeth and bones of
the bomber - for identification purposes.
Sources:
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Bassals,
Susan. “A Database Too Far?” New Scientist. March 10, 2002.
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Brahimi,
Rym. “Scientists Fears Over DNA Plan.” The Scientist. March 7, 2002.
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Candiotti,
Susan. “Breakthrough May Be Close In Anthrax Probe.” CNN. January 21,
2002.
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Johnston,
David & Risen, James. “U.S. Wants DNA of ALL Detainees From
Afghanistan.” The New York Times. March 3, 2002.
See
also:
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